For the simulation requirements of space-based infrared detection images, amissile radiation simulation model was developed based on the governing equations of missileinternal and external flow field and the radiation calculation equation. An earth surfacebackground radiation simulation model was developed based on the GlobCover and therandom fractal algorithm. A coupling simulation method of entrance pupil radiaiton insatelite camera was proposed based on rigorous imaging geometric model. In addition, asimulation method of space-based infrared detection images for moving targets in complexearth surface background was proposed, coupling the models of optical system, detector andsignal processing in the imaging link of detection system. The simulation results reveal thatbased on the data of satelite orbit and missile trajectory, the proposed method can be appliedto achieve the continuous imaging simulation of the missile in the boosting phase